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A Clinical Appraisal of Pentapyrrolidinium (M&B 2050) in Hypertensive Patients

 Digital Record
Identifier: 101584929X43
Digital Object (text)

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Dates

  • Publication: April 1954

Extent

7 pages

Creator

Description

Here, Freis's team studied the effectiveness of pentapyrrolidinium (a ganglionic-blocking agent, also called pentolinium) as an antihypertensive treatment. They concluded that the drug had several advantages in the treatment of severe hypertension over another ganglionic-blocking agent, hexamethonium. The drug's attributes, longer duration of action, greater potency, and a more uniform response to oral administration, more than compensated for its... side effects and the frequent need to adjust dosage.

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Language of Materials

English

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