Skip to main content

Govt building

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure access Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Clinical Trial of Guanethidine, a New Type of Antihypertensive Agent

 Digital Record
Identifier: 101584929X49
Digital Object (text)

Go to file

Dates

  • Publication: August 1959

Extent

4 pages

Creator

Description

Throughout the 1950s and 1960s several ganglionic-blocking agents were introduced that provided a variety of options for clinicians treating high blood pressure. These agents reduced blood pressure by interfering with nerve impulses from the brain that constricted blood vessels. In this article, Freis and Frohlich reported that one of these agents, guanethidine, exhibited a potent, orthostatic, antihypertensive effect similar to other ganglionic-blocking agents.

Language of Materials

English

Additional Description

Original Profiles System Identifier

XFBBDJ

Source Category

Periodical

Frohlich, Edward D., and Edward D. Freis. "Clinical Trial of Guanethidine, a New Type of Antihypertensive Agent." The Medical Annals of the District of Columbia XXVIII, 8 (August 1959): 419-422. Article. 4 Images.

The Medical Annals of the District of Columbia

Physical Description

Physical Condition - Good

Subjects

Related Names

Creator

Source

Linked Records

Collecting Area Details

Collecting Area Details

Part of the Archives and Modern Manuscripts Collections Collecting Area

Contact:
8600 Rockville Pike
Bldg 38/1E-21, MSC 3819
Bethesda MD 20894 US
1-888-FINDNLM (1-888-346-3656)