The Distribution and Metabolism of Lysergic Acid Diethylamide

Digital Record

Identifier: 101584577X11

Staff Only

Digital Object (text)

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Dates

Publication: 14 March 1957

Extent

10 pages

Creator

Witkop, Bernhard, 1917- (Creator, Person)

Description

Late in the 1950s, Axelrod became interested in the distribution, excretion, metabolization and rate of "biotransformation" of lysergic acid diethylamide (LSD) by the body. In this first of several articles on the narcotic drug, he detailed the subcellular processes involved in the transformation of LSD, determined the order of concentrations of the drug in various tissues, determined that it was almost completely metabolized by the body, and found that their were considerable differences between various animal species in the rate of biotransformation of LSD.

Language of Materials

English

Additional Description

Original Profiles System Identifier

HHAAAK

Source Category

Periodical

Axelrod, Julius, Roscoe O. Brady, Bernhard Witkop, and Edward V. Evarts. "The Distribution and Metabolism of Lysergic Acid Diethylamide." Annals of the New York Academy of Sciences 66, (14 March 1957): 435-444. Article. 10 Images.

Annals of the New York Academy of Sciences