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Box 1
Container
Contains 30 Results:
Spiegel, Robert and Elliott Stupak, Jan. 9, 1987
File — Box: 1, Folder: 21
Scope and Contents
Institution: Schering-Plough. Topics: Interferon development; difference between working at Schering and NIH; FDA drug approval process, regulatory environment for risk-taking corporate industry; forecasting future applications for Inteferon, monoclonal antibodies; Schering's anti-cancer drug program, lymphokines; migration of young scientists from NIH to industry instead of academia; technicalities of production and patenting and speed to market competition; comparisons with Hoffman-La...
Dates:
Jan. 9, 1987
Sternbach, Leo, Jan. 29, 1987
File — Box: 1, Folder: 22
Scope and Contents
Institution: Hoffman-La Roche. Topics: 1930s educational background, studying in Vienna and Zurich; last visit to Poland Christmas 1938; Nazi occupation, anti-semitism, violence against him and his family in Krakow, gets job at La Roche in Basel 1940; Barrell and Bobst leadership at La Roche; first research projects, riboflavin, Xenical; move to Valium started with benzodiazepines and other compounds similar to chlorpromazine; clidinium bromide, self-testing at home; benzodiazepine work...
Dates:
Jan. 29, 1987
Stetten, DeWitt, Dec. 6, 1986
File — Box: 1, Folder: 23
Scope and Contents
Institution: NIH. Topics: Educational background; work at Columbia University, influence of German refugee biochemists and German research traditions, Hans Clarke; circle of New York institutions: Rockefeller, NYU, Cornell, Columbia; coming to NIDDK in 1959, research atmosphere of the time, how the labs operated; Arthur Kornberg, Leon Heppell, Bernard Horecker; Marshall Nirenberg and Severo Ochoa DNA race, energized entire campus, wasn't just Nirenberg's lab doing all the work; his work at...
Dates:
Dec. 6, 1986
Sweet, Charles and Arthur Datchett, Feb. 6, 1987
File — Box: 1, Folder: 24
Scope and Contents
Institution: Merck. Topics: ACE inhibitors, Vasotec; chemistry of thiol compounds; renin angiotensin system; historical importance of 1975 Gravas paper to hypertension research; Enalapril vs. Captopril, market share competition with Squibb; Sweet's history in cardiovascular field at Merck, Cleveland Clinic; Merck's strong position in the field
Dates:
Feb. 6, 1987
Tabor, Herbert, Dec. 16, 1986
File — Box: 1, Folder: 25
Scope and Contents
Institution: NIH/NIDDK. Topics: Educational background; Harvard, Columbia, Yale as centers of American biochemistry; Baird Hastings, DeWitt Stetten; first job as PHS Commissioned Officer in 1943 on board Coast Guard cutters; beginnings of NIH research community with Heppel, Horecker, Kornberg; lunch time seminars process; research environment in academia; anti-Semitism and war years, impact at Harvard, Yale, Columbia, why so many top biochemists came to Columbia; Southern gentleman culture...
Dates:
Dec. 16, 1986
Vita, Giulio, Feb. 5, 1987
File — Box: 1, Folder: 26
Scope and Contents
Institution: Bristol-Myers. Topics: How most new drugs are discovered by industry and not by academia; how hard it is to go from a lab to mass production, huge risks involved; industry involved in basic research to understand the underlying mechanisms of diseases, Bristol Myers on verge of breakthroughs in cancer research and infectious disease, genetic engineering and microbiology, receptorology, cell biology; where does this leadership value-set come from; importance of academia for new...
Dates:
Feb. 5, 1987
Waldmann, Thomas, Dec. 4, 1986
File — Box: 1, Folder: 27
Scope and Contents
Institution: NIH/NCI. Topics: Family genealogy; first interests in becoming a scientist; interface between basic science and clinical medicine; getting his start in immunology, intestinal lymphangiectasia research; collaborative culture of NIH; human suppressor cells discovery and research; molecular biology of immunoglobulin and T-cell receptor genes and interleukin-2 receptor to understand cell malignancy/leukemia, method for defining clonality as diagnostic tool; interleukin-2 or T-Cell...
Dates:
Dec. 4, 1986
Welch, Arnold, Nov. 22, 1986
File — Box: 1, Folder: 28
Scope and Contents
Institution: Sharpe and Dohme; Western Reserve; Squibb. Topics: Educational background, family genealogy; getting started in pharmacology with Carl and Gerty Cori in St. Louis; leaving Western Reserve for oncology program at Sharpe and Dohme, impact on career going to industry vs. academia; politics of pharmacology and Cori's research; difficulties of protein research; status of drug companies and industry research in 1940s, Merck, Sharpe and Dohme, Lilly; starting a research division from...
Dates:
Nov. 22, 1986
Wiseman, Edward, Feb. 13, 1987
File — Box: 1, Folder: 29
Scope and Contents
Institution: Pfizer. Topics: importance of information sharing in science, even in industry; human dimension of drug creation, bringing non-steroidal anti-inflammation research to Pfizer with Joe Lombardino in 1962; major arthritis treatment regimens and drugs during 1960s, human element of understanding the systemic disease as new piece of corporate strategy to strategically develop other drugs and therapies, commercial viability of that approach; discovering oxicams, Feldene and its...
Dates:
Feb. 13, 1987
Young, John P., Jan. 30, 1987
File — Box: 1, Folder: 30
Scope and Contents
Institution: Smith, Kline, French. Topics: Rhone-Poulenc corporate culture/character; joined company in 1952 just before getting chlorpromazine license; discovering its antipsychotic characteristics; history of other companies being offered chlorpromazine; internal skepticism and difficulties of developing the drug and antipsychotics as a business area in general, commercial viability of antipsychotic marketplace in 1950s; story of its first experimental use, demonstrable effect led to...
Dates:
Jan. 30, 1987