Skip to main content

The Distribution and Metabolism of Lysergic Acid Diethylamide

 Digital Record
Identifier: 101584577X11


  • Publication: 14 March 1957


10 Pages


Late in the 1950s, Axelrod became interested in the distribution, excretion, metabolization and rate of "biotransformation" of lysergic acid diethylamide (LSD) by the body. In this first of several articles on the narcotic drug, he detailed the subcellular processes involved in the transformation of LSD, determined the order of concentrations of the drug in various tissues, determined that it was almost completely metabolized by the body, and found that their were considerable differences between various animal species in the rate of biotransformation of LSD.

Language of Materials


Original Profiles System Identifier


Source Category


Axelrod, Julius, Roscoe O. Brady, Bernhard Witkop, and Edward V. Evarts. "The Distribution and Metabolism of Lysergic Acid Diethylamide." Annals of the New York Academy of Sciences 66, (14 March 1957): 435-444. Article. 10 Images.

Annals of the New York Academy of Sciences

Relation Category



Physical Description

Physical Condition - No Status

Collecting Area Details

Part of the Archives and Modern Manuscripts Collection Collecting Area

8600 Rockville Pike
Bldg 38/1E-21, MSC 3819
Bethesda MD 20894 US
1-888-FINDNLM (1-888-346-3656)