Treatment of Essential Hypertension with Chlorothiazide (Diuril): Its Use Alone and Combined with Other Antihypertensive Agents

Digital Record

Identifier: 101584929X135

Staff Only

Digital Object (text)

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Dates

Publication: 11 January 1958

Extent

4 pages

Creator

Freis, Edward D. (Creator, Person)

Description

In this article, Freis and his colleagues reported the results of their initial trials of the new diuretic, chlorothiazide, in patients with moderate hypertension. Chlorothiazide often reduced blood pressure when used alone; when used together with other antihypertensive drugs, it potentiated their effects, so that lower doses of the other drugs could be used, and side-effects could be avoided. Chlorothiazide represented a major advance in the treatment of hypertension.

Language of Materials

English

Additional Description

Original Profiles System Identifier

XFBBJP

Source Category

Periodical

Freis, Edward D., Annemarie Wanko, Ilse M. Wilson, and Alvin E. Parrish. "Treatment of Essential Hypertension with Chlorothiazide (Diuril): Its Use Alone and Combined with Other Antihypertensive Agents." Journal of the American Medical Association 166, 2 (11 January 1958): 137-140. Article. 4 Images.

Journal of the American Medical Association