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A Double Blind Control Study of Antihypertensive Agents: I. Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglionic Blocking Agents, Chlorisondamine, Mecamyamine, and Pentolinium Tartrate

 Digital Record
Identifier: 101584929X61

Digital Object (text)

Dates

  • Publication: July 1960

Extent

16 Pages

Description

In 1956, Freis and a group of physicians in several Veterans Administration hospitals organized a cooperative study group to evaluate antihypertensive agents under well-controlled conditions. In this first of three articles, they reported that various therapeutic regimens were compared in a double-blind control study on 326 hypertensive patients, 232 of whom completed a full year of treatment. The group found that a combination of reserpine (a ganglionic-blocking agent) and hydralazine (a vasodilator) was far more effective than placebos or reserpine alone.

Language of Materials

English

Additional Description

Original Profiles System Identifier

XFBBDY

Source Category

Periodical

Veterans Administration Cooperative Study Group on Antihypertensive Agents. "A Double Blind Control Study of Antihypertensive Agents: I. Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglionic Blocking Agents, Chlorisondamine, Mecamyamine, and Pentolinium Tartrate." Archives of Internal Medicine 106, (July 1960): 81-96. Article. 16 Images.

Archives of Internal Medicine

Relation Category

UI (NLM)

XFBBDZ

UI (NLM)

XFBBFB

Physical Description

Physical Condition - Good

Subjects

Related Names

Source

Linked Records

Collecting Area Details

Collecting Area Details

Part of the Archives and Modern Manuscripts Collection Collecting Area

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