Double Blind Control Study of Antihypertensive Agents: II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate
- Publication: August 1962
In 1956, Freis and a group of physicians in several Veterans Administration hospitals organized a cooperative study group to evaluate antihypertensive agents under well-controlled conditions. In this second of three articles, they confirmed some of the general findings of the first report, that a regimen of reserpine (a ganglionic-blocking agent) combined with hydralazine (a vasodilator) produced far better results than the use of ganglionic-blocking agents alone.
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