Mecamylamine, a New, Orally Effective, Hypotensive Agent

Freis and Wilson reported here on mecamylamine, a new, orally-administered, ganglionic-blocking agent. They determined that mecamylamine appeared to be a very effective antihypertensive agent, especially when combined with small doses of reserpine (another ganglionic-blocker) or hydralazine (a vasodilator). Mecamylamine was long considered an ideal treatment for moderately and severely hypertensive patients.

NOTE: Scanned item is a reprint. Original article is on pp. 551-561.