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Letter from A. M. Pappenheimer, Jr., University of Pennsylvania School of Medicine to Michael Heidelberger

 Digital Record
Identifier: 101584940X207

Dates

  • 23 October 1940

Extent

2 Pages

Creator

Description

In this exchange of letters Heidelberger and Pappenheimer discussed hypotheses and evidence regarding the location of the sites at which antibody molecules (later shown to be Y-shaped) bind to antigens. One hypothesis, proposed by the preeminent physical chemist Linus Pauling and discussed in this letter, held that these binding sites were located at the ends of a symmetrical molecule.

Language of Materials

English

Original Profiles System Identifier

DHBBND

Relation Category

UI (NLM)

DHBBNF

Physical Description

Physical Condition - Good

Collecting Area Details

Part of the Archives and Modern Manuscripts Collection Collecting Area

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