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The Use of Affinity Chromatography in the Study of Protein Folding

 Digital Record
Identifier: 101584571X156


  • Publication: 1983


7 Pages



This article, which includes handwritten notes by Anfinsen, provided an overview of the use of affinity chromatography in the study of protein folding and its importance for vaccine production. Anfinsen briefly reviewed the use of affinity chromatography as a tool in the study of the interaction between peptides and antibodies, noting that at times the technique revealed that fragments of a protein molecule bind with monospecific antibodies, thus indicating that those fragments, which otherwise appeared to lack structure, occupied an ordered structure for at least a portion of their existence.

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Original Profiles System Identifier


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Anfinsen, Christian B. "The Use of Affinity Chromatography in the Study of Protein Folding." Affinity Chromatography and Biological Recognition, edited by I. Chaiken, M. Wilchek, and I. Parikh. Academic Press, 1983. Pp. 355-361. Article. 7 Images.

Physical Description

Physical Condition - Good

Collecting Area Details

Part of the Archives and Modern Manuscripts Collection Collecting Area

8600 Rockville Pike
Bldg 38/1E-21, MSC 3819
Bethesda MD 20894 US
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