Skip to main content
To request boxes, please see the Reference Librarian to submit the collection and box number(s) via LocatorPlus.

Some Relationships of Structure to Function in Ribonuclease

 Digital Record
Identifier: 101584571X166

Dates

  • Publication: 4 September 1959

Extent

9 Pages

Description

This study by White and Anfinsen on the renaturation of fully denatured ribonuclease, or RNase, required subsequent supporting investigations to establish what came to be called the "thermodynamic hypothesis." Here they reported that RNase activity depended upon a variety of structural features, but noted that it could be inferred from the results of their experimentation that only a small part of the enzyme molecule, what they termed the "active center," was necessary for catalyst.

Language of Materials

English

Original Profiles System Identifier

KKBBKY

Source Category

Periodical

White, F. H. Jr, and Christian B. Anfinsen. "Some Relationships of Structure to Function in Ribonuclease." Annals of the New York Academy of Sciences 81, 3 (4 September 1959): 515-523. Article. 9 Images.

Annals of the New York Academy of Sciences

Physical Description

Physical Condition - Good

Collecting Area Details

Part of the Archives and Modern Manuscripts Collection Collecting Area

Contact:
8600 Rockville Pike
Bldg 38/1E-21, MSC 3819
Bethesda MD 20894 US
1-888-FINDNLM (1-888-346-3656)